ABSTRACT
Objective :To comprehensively analyze therapeutic effect of clopidogrel combined aspirin on acute myo-cardial infarction (AMI).Methods :A total of 100 AMI patients treated in our hospital were selected ,and equally divided into clopidogrel group and combined treatment group (received clopidogrel combined aspirin ).Both groups received routine treatment for 4 weeks .Total effective rate ,platelet aggregation rate (PAR) ,coronary recanaliza-tion time ,prothrombin time (PT) ,left ventricular ejection fraction (LVEF) and incidence rate of cardiovascular e-vents during hospitalization were compared between two groups .Results :Total effective rate of combined treatment group was significantly higher than that of clopidogrel group (96. 00% vs.80.00%, P＝0.014).Compared with clopidogrel group after treatment ,there were significant reductions in PAR [ (47.63 ± 7.83)% vs.(38.45 ± 8.55)%] ,incidence rate of cardiovascular events (24.00% vs.4.00%) and coronary recanalization time [(45.44 ± 4.42) vs.(41.93 ± 5.85)] ,P and significant rise in LVEF [ (48.56 ± 5.79)% vs.(55.51 ± 6.44)%] in combined treatment group , P＜0. 01 all.Conclusion : The clinical effect of clopidogrel combined with aspirin in the treatment of acute myocardial infarction is significant .
ABSTRACT
Objective:To analyze therapeutic effect of comprehensive rehabilitation therapy on patients with hypertension. Methods:A total of 100 patients with hypertension treated in our hospital were enrolled.According to random number ta-ble,they were randomly and equally divided into routine treatment group and comprehensive rehabilitation therapy group (received comprehensive rehabilitation therapy based on routine treatment).After one month,blood pressure,body mass index(BMI),6min walking distance(6MWD),left ventricular ejection fraction(LVEF)before and after treatment,and acute onset times of hypertension during treatment were observed and compared between two groups.Results:Compared with before treatment,there were significant reductions in blood pressure,and significant rise in 6MWD and LVEF after treatment in two groups,P<0.01 all;compared with routine treatment group after treatment,there were significant re-ductions in blood pressure[(136.53 ± 9.25)/(83.52 ± 5.24)mmHg vs.(118.53 ± 6.53)/(78.42 ± 6.53)mmHg], BMI[(23.43 ± 3.12)kg/m2vs.(20.53 ± 2.24)kg/m2]and mean times of acute onset[(6.8 ± 3.5)times vs.(3.2 ± 1.2) times],and significant rise in 6MWD[(325.12 ± 65.39)m vs.(368.34 ± 89.52)m],LVEF[(55.34 ± 4.22)% vs. (60.95 ± 2.53)%]in comprehensive rehabilitation therapy group after treatment,P<0.01 all.Conclusion:Comprehen-sive rehabilitation therapy possesses good therapeutic effect on patients with hypertension.It can significantly decrease blood pressure,increase exercise capacity,improve cardiac function and reduce acute onset times of hypertension in these patients,which is worth extending in clinic.